SS-31

Peptide, Fat Loss & Metabolism, Recovery & Regeneration

SS-31

Peptide, Fat Loss & Metabolism, Recovery & Regeneration

SS-31

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$49.95

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QuantityDiscountDiscounted price
3 - 45%$47.45
5 - 67%$46.45
7 - 89%$45.45
9 +11%$44.46

Research Use Only

These products are for laboratory research only and not intended for medical use. They are not FDA-approved to diagnose, treat, cure, or prevent any disease. By purchasing, you certify they will be used solely for research and not for human or animal consumption.

What is it?

SS-31 (also known as Elamipretide) is a synthetic tetrapeptide designed for research into mitochondrial protection and cellular energy regulation. It has been studied for its ability to stabilize mitochondrial membranes, reduce oxidative stress, and improve ATP production in biological models. Researchers have investigated SS-31 for its potential role in mitochondrial dysfunction, cellular aging, and metabolic health, as it may support more efficient energy conversion and resistance to oxidative damage.

Certificate of Analysis

This research peptide is 99% purity. Certificate: EPS SS-31 10mg

Frequently Asked Questions

Does the product come with instructions?

Products from Elite Miami Peptides do not include usage instructions, as they are strictly for in vitro research and prohibited by law for human or animal use. Misuse or unlawful application will result in permanent denial of service.

Each vial contains exactly what’s indicated on the label. For instance, a 10mg vial contains precisely 10mg of lyophilized peptide. Researchers may divide it into smaller research portions—such as four 2.5mg aliquots—but the total content remains the same.

Yes. All peptides are supplied in lyophilized powder form and do not come reconstituted. Any extra materials required for research, such as solvents or diluents, must be obtained separately.

When stored as a dry powder, peptides remain stable for up to 2 years.
Once reconstituted, the solution should be kept refrigerated and is typically stable for up to 2 months under proper storage conditions.

Overview

SS-31 is a cell-permeable mitochondria-targeting peptide that binds selectively to cardiolipin, a phospholipid found within the inner mitochondrial membrane. This interaction is thought to preserve mitochondrial structure and function, allowing for more efficient ATP synthesis and reduced oxidative stress. Scientific studies suggest SS-31 may mitigate cellular damage caused by reactive oxygen species (ROS), while also helping maintain membrane integrity during metabolic stress. It is frequently used in research related to cellular bioenergetics, metabolic decline, and oxidative aging models. (Adapted from Szeto et al., 2011; Birk et al., 2014)

Explanation

SS-31 is a research compound studied for how it may help cells produce and use energy more efficiently. In lab settings, scientists have found that it can help protect mitochondria — the “power plants” of cells — from damage caused by stress or aging. By keeping mitochondria healthy, SS-31 may help improve cellular energy output, reduce oxidative stress, and support better overall cell performance in experimental models.

⚠️ Disclaimer: this product is not approved for medical use and is not intended to diagnose, treat, or prevent any disease. All information provided is for educational and research purposes only, and this product must never be used in humans or animals.

History

The development of SS-31 stems from decades of research on mitochondrial-targeted antioxidants. Dr. Hazel H. Szeto first introduced the compound as part of the Szeto-Schiller (SS) peptide series, which were designed to cross cell membranes and accumulate in mitochondria. Initial studies demonstrated SS-31’s unique ability to bind to cardiolipin, protect mitochondrial structure, and enhance ATP synthesis. Since then, SS-31 has become a central focus in mitochondrial biology research, particularly for energy metabolism and age-related cellular dysfunction. (Adapted from Szeto et al., 2008; Zhao et al., 2004)

Structure

CAS #: 127445-25-4 Molecular Formula: C₄₆H₈₆N₁₂O₆ Molecular Weight: 958.3 g/mol Sequence: D-Arg-Dmt-Lys-Phe-NH₂ PubChem ID: 54774917

Research Findings

SS-31 has been widely studied for its antioxidant, mitochondrial, and cytoprotective effects in research environments. By binding to mitochondrial membranes, it enhances electron transport efficiency and helps mitigate oxidative damage. Key Areas of Research: Mitochondrial Protection: Stabilization of cardiolipin and membrane potential Energy Regulation: Improved ATP synthesis and bioenergetic balance Oxidative Stress: Reduction of ROS-related damage and inflammation Cellular Longevity: Protection of mitochondrial DNA and structure Together, these findings suggest SS-31 is a valuable tool for exploring the mechanisms behind mitochondrial dysfunction, aging, and metabolic disorders in laboratory models. (Summarized from Birk et al., 2014; Zhao et al., 2004; Szeto et al., 2011)

Explanation

In simpler terms, researchers use SS-31 to study how to keep cells’ energy centers (mitochondria) working properly. It helps scientists understand how to protect cells from aging and oxidative stress and how to improve energy balance at the cellular level. Because mitochondrial health is tied to energy, endurance, and cell function, SS-31 has become one of the most important compounds for energy and longevity research.

References

Szeto, H.H. et al. (2008). Mitochondria-targeted peptides protect against mitochondrial dysfunction. Am J Physiol Cell Physiol, 295(3), C718–C727. Birk, A.V. et al. (2014). The mitochondrial-targeted peptide SS-31 enhances ATP synthesis and reduces oxidative damage. J Biol Chem, 289(11), 7929–7937. Zhao, K. et al. (2004). Cell-permeable peptide antioxidants targeted to mitochondria. J Biol Chem, 279(33), 34682–34690. Szeto, H.H. (2011). Therapeutic potential of mitochondria-targeted peptides in oxidative disorders. Pharmacol Ther, 131(2), 133–143.

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Research Use Only

These products are for laboratory research only and not intended for medical use. They are not FDA-approved to diagnose, treat, cure, or prevent any disease. By purchasing, you certify they will be used solely for research and not for human or animal consumption.

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Research Use Only

All compounds from Elite Miami Peptides are intended strictly for laboratory research purposes.

They are not for human use, consumption, or therapeutic applications.
Products are supplied exclusively to qualified professionals working in compliance with all applicable laws and regulations.