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Retatrutide

Retatrutide

Peptide, Fat Loss & Metabolism

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Retatrutide

Retatrutide

Peptide, Fat Loss & Metabolism

Retatrutide

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Price range: $129.95 through $199.95

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QuantityDiscountDiscounted price
3 - 45%-
5 - 67%-
7 - 89%-
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Research Use Only

These products are for laboratory research only and not intended for medical use. They are not FDA-approved to diagnose, treat, cure, or prevent any disease. By purchasing, you certify they will be used solely for research and not for human or animal consumption.

What is it?

Retatrutide is a research-grade synthetic peptide designed to interact with GLP-1, GIP, and glucagon receptors — three major pathways involved in metabolic regulation. Early experimental models suggest it plays a role in improving insulin sensitivity, supporting energy balance, and influencing lipid metabolism through coordinated receptor activity. This compound represents a new generation of triple-agonist peptides being studied for their combined impact on metabolic signaling.

Certificate of Analysis

This research peptide is 99% purity. Certificate: EPS Retatrutide 10mg

Frequently Asked Questions

Does the product come with instructions?

Products from Elite Miami Peptides do not include usage instructions, as they are strictly for in vitro research and prohibited by law for human or animal use. Misuse or unlawful application will result in permanent denial of service.

Each vial contains exactly what’s indicated on the label. For instance, a 10mg vial contains precisely 10mg of lyophilized peptide. Researchers may divide it into smaller research portions—such as four 2.5mg aliquots—but the total content remains the same.

Yes. All peptides are supplied in lyophilized powder form and do not come reconstituted. Any extra materials required for research, such as solvents or diluents, must be obtained separately.

When stored as a dry powder, peptides remain stable for up to 2 years.
Once reconstituted, the solution should be kept refrigerated and is typically stable for up to 2 months under proper storage conditions.

Overview

Retatrutide is a laboratory research peptide that scientists are studying for its potential effects on energy balance, metabolism, and fat utilization. In research settings, Retatrutide has been shown to activate three major biological pathways — GLP-1, GIP, and glucagon receptors — which together play an essential role in how the body manages blood sugar, appetite, and energy expenditure. By stimulating these pathways simultaneously, researchers have observed enhanced glucose regulation, increased energy use, and improved fat metabolism in experimental models. These findings suggest that Retatrutide may be an important compound for advancing understanding of how hormones influence weight regulation, insulin sensitivity, and metabolic health.

Explanation

Retatrutide is a synthetic multi-receptor peptide agonist that simultaneously targets GLP-1, GIP, and glucagon receptors. These pathways are associated with energy regulation, appetite control, and metabolic rate in biological systems. Preclinical and early human models have shown that activating these receptors together can promote greater metabolic efficiency, insulin responsiveness, and fat utilization. Ongoing studies continue to explore its role in metabolic adaptation, body composition, and energy expenditure under controlled laboratory conditions. (Based on Jastreboff, A.M. et al., 2023)

⚠️ Disclaimer: this product is not approved for medical use and is not intended to diagnose, treat, or prevent any disease. All information provided is for educational and research purposes only, and this product must never be used in humans or animals.

History

The development of Retatrutide builds upon decades of exploration into incretin-based signaling, which includes hormones like GLP-1 and GIP. Earlier research into these hormones demonstrated benefits in glucose control, appetite regulation, and lipid metabolism. By combining GLP-1, GIP, and glucagon receptor activity in one molecule, Retatrutide represents a triple-agonist approach, expanding upon prior generations of incretin mimetics and dual agonists. (Adapted from Coskun, T. et al., 2023)

Structure

Molecular Formula: C₁₈₉H₂₈₆N₄₆O₅₉ Molecular Weight: 4245.68 g/mol Sequence Length: 51 amino acids PubChem ID: CID166533632

Research Findings

Retatrutide has been studied in both preclinical and metabolic modeling environments, showing promising activity in regulating glucose metabolism, lipid oxidation, and systemic energy expenditure. Its ability to act on three metabolic hormone receptors makes it unique among peptides under investigation for metabolic disorder research. Primary Research Observations: Metabolic Efficiency: Improved glucose control and insulin sensitivity Energy Regulation: Enhanced energy expenditure in experimental models Endocrine Function: Interaction with GLP-1, GIP, and glucagon receptors Systemic Effects: Potential for balanced multi-receptor signaling Overall, data from laboratory settings indicate that Retatrutide could serve as a valuable model for studying integrated metabolic pathways and the physiological coordination of energy use, appetite, and insulin signaling. (Reinterpreted from Jastreboff et al., 2023, NEJM)

Explanation

In simple terms, researchers studying Retatrutide have found that it may help the body burn energy more efficiently, use sugar more effectively, and support healthier metabolic function in laboratory settings. It appears to work by activating three hormonal pathways at once — the same ones involved in controlling appetite, blood sugar, and energy levels. These effects make it an exciting area of study for scientists exploring new ways to understand and model metabolic diseases, insulin resistance, and obesity.

References

Jastreboff, A.M. et al. (2023). Triple hormone receptor agonist retatrutide in obesity and diabetes management. New England Journal of Medicine, 389(5), 401–412. Coskun, T. et al. (2023). Retatrutide: A triple hormone receptor agonist for obesity and diabetes. Diabetes, 72(8), 1463–1478.

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Research Use Only

These products are for laboratory research only and not intended for medical use. They are not FDA-approved to diagnose, treat, cure, or prevent any disease. By purchasing, you certify they will be used solely for research and not for human or animal consumption.

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Research Use Only

All compounds from Elite Miami Peptides are intended strictly for laboratory research purposes.

They are not for human use, consumption, or therapeutic applications.
Products are supplied exclusively to qualified professionals working in compliance with all applicable laws and regulations.