KPV

Cell Signaling Research

KPV

Cell Signaling Research

KPV

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Original price was: $74.95.Current price is: $58.95.

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Research Use Only

These products are for laboratory research only and not intended for medical use. They are not FDA-approved to diagnose, treat, cure, or prevent any disease. By purchasing, you certify they will be used solely for research and not for human or animal consumption.

What is it?

KPV is a synthetic research peptide consisting of the tripeptide sequence Lysine–Proline–Valine (Lys-Pro-Val). It is derived from the C-terminal region of the melanocortin hormone α-MSH and is commonly studied in models of inflammation, epithelial barrier function and tissue integrity. Each vial of KPV 10mg provides KPV as a lyophilized powder intended exclusively for laboratory research use.

Certificate of Analysis

KPV is manufactured under controlled conditions and released at high purity, typically ≥98–99% by HPLC and/or LC-MS. The lot-specific Certificate of Analysis confirms: Identity of the peptide (KPV, Lys-Pro-Val) Purity profile and chromatograms Peptide content per vial (10mg total KPV as specified by the manufacturer) Appearance (white to off-white lyophilized powder) Residual solvent and moisture content within internal limits This material is labeled strictly for research use only, not for human consumption.

Frequently Asked Questions

Does the product come with instructions?

Products from Elite Miami Peptides do not include usage instructions, as they are strictly for in vitro research and prohibited by law for human or animal use. Misuse or unlawful application will result in permanent denial of service.

Each vial contains the quantity of lyophilized research material indicated on the product label. Refer to the lot-specific Certificate of Analysis for identity and purity information.

Yes. All peptides are supplied in lyophilized powder form and do not come reconstituted. Any extra materials required for research, such as solvents or diluents, must be obtained separately.

When stored as a dry powder, peptides remain stable for up to 2 years.
Once reconstituted, the solution should be kept refrigerated and is typically stable for up to 2 months under proper storage conditions.

Overview

KPV is a minimal α-MSH–derived fragment that retains key anti-inflammatory and pro-resolving properties in experimental systems. It has been studied for its ability to modulate NF-κB signalling, down-regulate selected pro-inflammatory cytokines and support epithelial barrier markers in gut, skin and mucosal models. Because of its small size and simple structure, KPV is often used as a tool peptide to dissect melanocortin-related pathways without the broader receptor activity of full-length α-MSH.

Explanation

In simple terms, KPV is a short lab-only peptide built from just three amino acids. It is based on a small part of a natural hormone involved in inflammation control. Researchers use it to see how turning “down” certain inflammatory signals and supporting barrier tissues (like the gut or skin lining) might affect different experimental models. It is not a medicine or supplement and is supplied only for controlled research, not for human use.

⚠️ Disclaimer: this product is not approved for medical use and is not intended to diagnose, treat, or prevent any disease. All information provided is for educational and research purposes only, and this product must never be used in humans or animals.

History

KPV emerged from early work on melanocortin peptides, where scientists discovered that short fragments from the C-terminal region of α-MSH could reproduce many of its anti-inflammatory effects. Since then, KPV has been evaluated in a variety of in-vitro and animal studies, including models of colitis, dermatitis and wound healing, as a compact probe for melanocortin-related inflammation pathways.

Structure

Sequence: Lys-Pro-Val (KPV). Peptide length: 3 amino acids. KPV is a tripeptide corresponding to the C-terminal sequence of α-MSH and is investigated as an experimental probe of melanocortin-related cellular signaling.

Research Findings

In preclinical models, KPV has been reported to: Reduce levels of selected pro-inflammatory cytokines (such as TNF-α and IL-6) Modulate NF-κB and related signalling pathways in immune and epithelial cells Support epithelial barrier integrity markers in gut and skin models Improve histologic scores and tissue appearance in experimental colitis and dermatitis setups These findings are specific to controlled in-vitro and in-vivo research models and may vary depending on dose, formulation, route and study design.

Explanation

Put simply, KPV is used when scientists want to test a focused, short peptide that “calms down” certain inflammation signals and helps barrier tissues behave more normally in lab models. Results so far are promising in early research settings, but they are experimental only and do not prove safety or effectiveness for any disease or condition in humans.

References

– Experimental studies evaluating KPV as an α-MSH–derived tripeptide in inflammation and epithelial barrier models. – Reviews on melanocortin peptides and their small fragments in immune modulation and tissue-repair research.

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Research Use Only

These products are for laboratory research only and not intended for medical use. They are not FDA-approved to diagnose, treat, cure, or prevent any disease. By purchasing, you certify they will be used solely for research and not for human or animal consumption.

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Research Use Only

All compounds from Elite Miami Peptides are intended strictly for laboratory research purposes.

They are not for human use, consumption, or therapeutic applications.
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