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Epitalon

Epitalon

Cellular Senescence Research

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Epitalon

Epitalon

Cellular Senescence Research

Epitalon

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Original price was: $94.95.Current price is: $68.95.

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Research Use Only

These products are for laboratory research only and not intended for medical use. They are not FDA-approved to diagnose, treat, cure, or prevent any disease. By purchasing, you certify they will be used solely for research and not for human or animal consumption.

What is it?

Epitalon is a synthetic tetrapeptide investigated in experimental models involving telomerase activity, gene-expression pathways, oxidative signaling and cellular senescence. Research has also examined associations with circadian-related molecular processes.

Certificate of Analysis

This research peptide is 99% purity. Certificate: EPS Epitalon 50mg

Frequently Asked Questions

Does the product come with instructions?

Products from Elite Miami Peptides do not include usage instructions, as they are strictly for in vitro research and prohibited by law for human or animal use. Misuse or unlawful application will result in permanent denial of service.

Each vial contains the quantity of lyophilized research material indicated on the product label. Refer to the lot-specific Certificate of Analysis for identity and purity information.

Yes. All peptides are supplied in lyophilized powder form and do not come reconstituted. Any extra materials required for research, such as solvents or diluents, must be obtained separately.

When stored as a dry powder, peptides remain stable for up to 2 years.
Once reconstituted, the solution should be kept refrigerated and is typically stable for up to 2 months under proper storage conditions.

Overview

Epitalon is a research peptide that has been studied for its influence on cellular senescence, gene expression, and oxidative signaling. Preclinical studies have examined its interaction with telomerase enzyme activity and chromosomal stability in laboratory models. Researchers have also explored Epitalon in relation to melatonin-related and circadian-rhythm molecular processes in experimental systems. (Adapted from Khavinson et al., 2003; Anisimov et al., 2004)

Explanation

Epitalon is a research compound that scientists are studying to understand how cells age and replicate in laboratory models. In experiments, it is examined for its interaction with telomerase, the enzyme involved in maintaining chromosome ends (telomeres) — a key part of cell division. Researchers have also studied its relationship with oxidative signaling and circadian-related molecular processes in laboratory models.

⚠️ Disclaimer: this product is not approved for medical use and is not intended to diagnose, treat, or prevent any disease. All information provided is for educational and research purposes only, and this product must never be used in humans or animals.

History

Epitalon was developed in the 1980s and 1990s by Professor Vladimir Khavinson and colleagues at the St. Petersburg Institute of Bioregulation and Gerontology in Russia. It was part of an ongoing effort to study peptide bioregulators — short amino acid sequences studied in relation to biological regulation and cellular senescence mechanisms. Since its discovery, Epitalon has been one of the most frequently referenced peptides in cellular senescence and gerontology research, particularly for its role in telomere biology and gene expression modulation. (Adapted from Khavinson et al., 2001; Khavinson & Anisimov, 2003)

Structure

CAS #: 307297-39-8 Molecular Formula: C₁₄H₂₂N₄O₉ Molecular Weight: 390.35 g/mol Sequence: Ala-Glu-Asp-Gly PubChem ID: 122097

Research Findings

Epitalon has been examined in numerous experimental and preclinical models, particularly those investigating cellular senescence, oxidative processes, and gene regulation. Research has examined its relationship with chromosome integrity and antioxidant signaling mechanisms. Key Areas of Research: Telomere Maintenance: Telomerase enzyme expression Cellular Senescence: DNA replication and stability models Endocrine Modulation: Melatonin and circadian-rhythm signaling Oxidative Signaling: Antioxidant activity in biological tissue models Together, these findings make Epitalon a compound of interest for cellular senescence research aimed at understanding the molecular mechanisms behind cell aging. (Summarized from Anisimov et al., 2003; Khavinson et al., 2004)

Explanation

In simple terms, scientists are studying Epitalon to help explain how cells age and replicate in laboratory models. It is examined in relation to cell replication and chromosomal stability, which is why it’s often called a “cellular senescence research peptide.” Researchers also study its role in circadian-related molecular processes, such as melatonin signaling, in experimental systems.

References

Khavinson, V.K. et al. (2001). Epitalon peptide regulates telomerase activity and extends cellular lifespan in laboratory models. Biogerontology, 2(3), 193–199. Anisimov, V.N. et al. (2003). Effect of Epithalamin and Epitalon on lifespan and tumor development in rodents. Mech Ageing Dev, 124(3), 475–482. Khavinson, V.K. & Anisimov, V.N. (2004). Peptide bioregulators and the aging process: Mechanisms of action and experimental findings. Ann N Y Acad Sci, 1019, 391–396.

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Research Use Only

These products are for laboratory research only and not intended for medical use. They are not FDA-approved to diagnose, treat, cure, or prevent any disease. By purchasing, you certify they will be used solely for research and not for human or animal consumption.

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